RSI

Medical Abbreviation
RSI

RSI stands for Rapid Sequence Intubation.

What does RSI mean?

a fast method of placing a breathing tube using sedation and a paralytic together

RSI stands for rapid sequence intubation, a method of quickly securing the airway by giving a sedative and a muscle relaxant (paralytic) in close succession, then placing a breathing tube. It is used in emergencies when a patient needs urgent airway control and is at risk of aspirating stomach contents. The technique is designed to create the best conditions for intubation while keeping the time the airway is unprotected as short as possible. RSI is performed by trained clinicians in emergency and critical care settings.

When is RSI used?

RSI is used in emergency departments, intensive care, and pre-hospital care when urgent airway control is needed.

Frequently asked questions

What does RSI stand for?

RSI stands for rapid sequence intubation, a fast method of placing a breathing tube using sedation and a paralytic together.

Why is RSI used?

It is used in emergencies when a patient needs urgent airway control and is at risk of aspirating stomach contents.

What drugs are used in RSI?

A sedative to induce unconsciousness and a muscle relaxant, or paralytic, given in close succession.

Who performs RSI?

Trained clinicians in emergency departments, intensive care units, and pre-hospital settings.

Related abbreviations

ACLS · ROSC · ABG

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Study reference only — not medical advice. Always consult qualified sources and supervisors for clinical decisions.
Medically reviewed by Syed Shahab Ullah, BSN · Last reviewed: October 2026